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Hedgehog  KaraGypsy wrote about 1 year ago

My INR levels have been so frustrating. I take 10 mg Sunday, Monday, Wednesday and Friday and 7.5 mg Tuesday, Thursday, and Saturday. As of 6/7/2016 my INR levels were at a 1.8. they have been as high as 4.1 and as low as 1.3 Please help!!!!

Category: INR

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Iam killer dog  austin - - posted about 1 year ago

HI.... SAME HERE BUT MUCH LOWER DOSE OF WARFARIN... 2.5 MG A DAY. I AM 85 YEARS OLD. HAD BLOOD CLOT LAST SEPT. THEN OPEN HEART SURGERY ON 2/26/2016. MITRAL VALVE REPAIRED AND ONE OVER PASS. SO.. ON WARFARIN BEFORE SURGERY. MY INR... UP AND DOWN, IP AND DOWN,... I ASKED MD IF I COULD GET OFF WARFARIN...SHE SAID "HIGH RISK OF STROKE" BUT THIS INCONSISTENT INR HAS BEEN GOING ON FOR MONTHS. WHY ???? I DON'T UNDERSTAND. THANK YOU. GOD BLESS. AUSTIN

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Wolf  Pavan - - posted about 1 year ago

I'm sorry you're going through this.

Here's some information from this page that could help you (http://inrtracker.com/inr-levels/inr-1.3)

Supplements That Decrease your INR13

Supplement Recommendations/Comments
CoQ10 Structurally similar to Vitamin K and, therefore, may need modest warfarin dose adjustment: Check INR within 2 weeks of starting supplement.
Flaxseed May impair absorption of warfarin--separate administration
Ginseng
Goldenseal
Psyllium/Fiber May impair absorption of warfarin--separate administration
St Johns Wort
Vitamin K Be consistent with supplements and multivitamins containing vitamin K
Drugs That Decrease Your INR11

Drug Brand Name
Aprepitant Emend©
Armodafinil Nuvigil©
Bosentan Tracleer©
Carbamazepine Carbatrol©, Epitol©, Equetro©, Tegretol©, Tegretol©– XR, Teril©
Cigarette Smoking
Efavirenz Atripla©, Sustiva©
Etravirine Intelence©
Modafinil Provigil©
Montelukast Singulair©
Nafcillin Nallpen© In Plastic Container
Omeprazole Nexium©, Prilosec©, Prilosec© OTC, Zegerid©, Zegerid© OTC
Phenobarbital Donnatal©
Phenytoin Dilantin©, Phenytek©
Pioglitazone Actoplus© Met, Actoplus© Met XR, Actos©, Duetact©, Oseni©
Prednisone Rayos©
Rifampin Rifadin©, Rifamate©, Rifater©, Rimactane©
Rufinamide Banzel©
Foods That Decrease Your INR13 Could be the reason for INR of 1.3

Food Recommendations/Comments
Ensure/Boost Contains ~25% of daily vitamin K and usually only significant if consuming several servings per day
Goose Liver Avoid due to unpredictable influence of vitamin K2
Green Tea May lower INR in large (i.e. >1 gallon/day) quantities
Liver Meats OK to eat, but treat like a vitamin K food
Nopales (Cactus) OK to eat, but treat like a high vitamin K food
Soy Products OK to eat, but treat like a vitamin K food
Alcohol And Your INR

Binge drinking alcohol will bring your INR up. Drinking 1-2 drinks will bring your INR down.13

Avoid Mangos

You should avoid consumption of all foods with mango because the interaction is unclear and is different from patient to patient.13

Cranberry Juice and Grapefruit Juice

UC San Diego Anticoagulation Clinic recommends, in general, an interaction between warfarin and cranberry products is NOT expected. What they advise, as with everything, is moderation - have a glass, not a gallon of cranberry juice.

The same goes for grapefruit juice.13

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Kitty in a hammock  kbincali - (26) - posted about 1 year ago

Just wanted to say I'm sorry to hear about your challenges, I really don't have an answer. I am by no means an expert in this, having been on this med for just a month. The only thing that I've done since I started was to eat more frequently/consistently throughout the day and to track all my food for the last month on this site. I'm either cooking everything myself or just eating whole foods easily tracked. I'm not doing any additional exercise etc. My dosage has been 5mg every day, and I slowly went from 1.5 to 2.2 where I've been stable, eating 100-120mcg of V-K a day. I'm curious how/why your doses change on different days. Hope things get better for you.

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Fantasy avatar 7  Jaci - (11) - posted about 1 year ago

It depends on his clinician and what they believe is the best regimen for him to take. I calculated my own. 5mg daily and 6.25 on Wed. and Sat. I have been stable for over a year now. The way coumadin is calculated is you divide the weekly dosage by 7 and this gives you a daily dosage. When it is a fraction the extra coumadin is spread throughout the week. Because of diet, age, medication, and several other factors, some people require more coumadin than others.

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